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Single IRB Unlocked: IREx is the Key to Efficient Single IRB Review for Lead Study Teams

Single IRB review refers to the use of a single IRB to oversee and approve the ethical and regulatory aspects of a multi-site research study, instead of having each participating institution’s IRB conduct a separate review. This approach aims to reduce duplication of effort, increase efficiency, and ensure consistent review across all participating sites. IREx – the IRB Reliance Exchange – is a freely available web-based tool to help lead study teams manage the single IRB requirements and streamline communications.

During the presentation, we will intro new IREx features that have been added to reduce lead study team burden and streamline the process for relying site study teams. We will detail the single IRB workflow using IREx, highlight new features, and share resources and lessons learned to minimize administrative burden, improve communication, and support an efficient single IRB review process.

This presentation is aimed at lead study teams involved in multi-site research projects using an academic single IRB. The goal is to provide lead study teams with insights and guidance on how the IREx platform can be used to navigate the complexities of single IRB review more efficiently and effectively.